Description

3,4-Dichloroisothiazole-5-carbonyl chloride is a highly reactive and versatile heterocyclic acid chloride building block. This compound is critical for the synthesis of advanced agrochemicals and pharmaceuticals, where it serves as a key precursor for introducing the functionalized isothiazole moiety. It is primarily sought after by research and development chemists and process engineers in the fine chemical, agrochemical, and pharmaceutical industries for constructing novel active ingredients and intermediates.

Application

• Agrochemical Intermediate: A key synthon for the development of novel fungicides, herbicides, and insecticides, leveraging the bioactivity of the isothiazole ring.
• Pharmaceutical Building Block: Used in the research and synthesis of potential drug candidates, particularly in medicinal chemistry for creating new heterocyclic scaffolds.
• Material Science Chemistry: Serves as a precursor for functional polymers or specialty chemicals requiring the dichloroisothiazole unit.
• Dye and Pigment Synthesis: Employed in the production of specialized colorants and functional dyes.
• Cross-Coupling Reactions: Acts as an electrophile in various palladium-catalyzed cross-coupling reactions to form complex molecules.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands or organocatalysts containing the isothiazole core.

Basic Information

Product Name	3,4-Dichloroisothiazole-5-carbonyl chloride
CAS No.	56914-82-0
Molecular Formula	C4Cl3NOS
Molecular Weight	212.45 g/mol
Synonyms	5-Chlorocarbonyl-3,4-dichloroisothiazole; 3,4-Dichloro-1,2-thiazole-5-carbonyl chloride; 3,4-Dichloroisothiazole-5-carboxylic acid chloride; Isothiazole-5-carbonyl chloride, 3,4-dichloro-; 3,4-Dichloro-δ2-1,2-thiazoline-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 3,4-Dichloroisothiazole-5-carbonyl chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition and moisture uptake. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.