Description

Adenosine 5',5'''-Triphosphoguanosine-3'''-Diphosphate is a specialized dinucleotide polyphosphate, a high-energy biochemical cofactor critical for advanced enzymatic and metabolic research. This compound serves as a key substrate and regulator in studies of nucleotide-dependent signaling pathways and energy transfer mechanisms. It is primarily utilized by research institutions and pharmaceutical developers focused on enzymology, molecular biology, and the development of novel therapeutic agents targeting cellular energy metabolism.

Application

• Enzymology Research: As a high-energy phosphate donor and substrate for studying ATP-dependent enzymes, kinases, and synthetases.
• Metabolic Pathway Analysis: Investigation of energy transfer and nucleotide cycling within complex cellular metabolic networks.
• Biochemical Assay Development: A critical component in the development of sensitive, high-throughput assays for enzyme activity and inhibitor screening.
• Signal Transduction Studies: Research into purinergic signaling pathways where dinucleotide polyphosphates act as extracellular signaling molecules.
• Pharmaceutical R&D: Used in target validation and mechanistic studies for drugs aimed at modulating cellular energy homeostasis.
• Reference Standard: Serves as an analytical standard for quality control and method validation in nucleotide analysis.

Basic Information

Product Name	Adenosine 5',5'''-Triphosphoguanosine-3'''-Diphosphate
CAS No.	56878-12-7
Molecular Formula	C20H26N10O22P5
Molecular Weight	964.37 g/mol
Synonyms	Ap5G; Adenosine(5')pentaphospho(5')guanosine; P1,P5-Di(adenosine-5') pentaphosphate, guanosine derivative; Gp5A; Dinucleoside pentaphosphate; Adenosine pentaphosphate guanosine; 5'-Adenylyl (5'→5')-guanosine pentaphosphate
EINECS	Contact for details

Quality Control

Our Adenosine 5',5'''-Triphosphoguanosine-3'''-Diphosphate is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term stability, store under inert atmosphere or desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	5.0 - 7.0
Endotoxin (LAL)	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.