Description

3-(Trifluoromethylthio)Phenacyl Bromide is a high-value organobromine building block characterized by its reactive phenacyl bromide and trifluoromethylthio functional groups. This compound is essential for introducing the highly lipophilic and metabolically stable SCF₃ moiety into target molecules, a key strategy in modern agrochemical and pharmaceutical design. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for synthesizing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates containing the trifluoromethylthioether group, which can enhance membrane permeability and metabolic stability.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides where the SCF₃ group improves bioactivity and environmental persistence.
• Material Science: Serves as a precursor for specialty monomers or ligands used in advanced polymers and catalysts.
• Chemical Synthesis: Versatile electrophile for nucleophilic substitution reactions, enabling the functionalization of heterocycles and complex organic scaffolds.
• Fluorine Chemistry: A valuable reagent for studying structure-activity relationships (SAR) in medicinal chemistry due to its distinct electronic properties.

Basic Information

Product Name	3-(Trifluoromethylthio)Phenacyl Bromide
CAS No.	56773-34-3
Molecular Formula	C₉H₆BrF₃OS
Molecular Weight	299.11 g/mol
Synonyms	2-Bromo-1-[3-[(trifluoromethyl)thio]phenyl]ethanone; 1-(3-(Trifluoromethylthio)phenyl)-2-bromoethanone; α-Bromo-3-((trifluoromethyl)thio)acetophenone; 3-(Trifluoromethylthio)phenacyl bromide; 2-Bromo-3'-(trifluoromethylthio)acetophenone; Phenacyl bromide, 3-(trifluoromethylthio)-; Ethanone, 2-bromo-1-[3-[(trifluoromethyl)thio]phenyl]-
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethylthio)Phenacyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate light conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.