Description

1-Fluoro-2,2-Diphenylcyclopropanecarbonyl Chloride is a highly reactive and versatile fluorinated cyclopropane building block. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel fluorinated scaffolds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially those incorporating fluorinated cyclopropane motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom and the strained cyclopropane ring can impart unique biological properties.
• Material Science Precursor: Serves as a building block for synthesizing specialized polymers, liquid crystals, or organic electronic materials that require fluorinated components.
• Medicinal Chemistry Research: Employed in high-throughput screening and combinatorial chemistry to create diverse compound libraries for drug discovery programs.
• Fluorine Chemistry Studies: Utilized as a model substrate in academic and industrial research to study reaction mechanisms involving fluorinated carbocations or nucleophilic substitutions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis organizations (CSOs) producing bespoke fluorinated compounds for client projects.

Basic Information

Product Name	1-Fluoro-2,2-Diphenylcyclopropanecarbonyl Chloride
CAS No.	56701-17-8
Molecular Formula	C16H12ClFO
Molecular Weight	274.72 g/mol
Synonyms	1-Fluoro-2,2-diphenylcyclopropanecarbonyl chloride; 2,2-Diphenyl-1-fluorocyclopropanecarbonyl chloride; 1-Fluoro-2,2-diphenylcyclopropane-1-carbonyl chloride; α-Fluoro-α,α-diphenylcyclopropanecarbonyl chloride; Cyclopropanecarbonyl chloride, 1-fluoro-2,2-diphenyl-; Fluorodiphenylcyclopropanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Fluoro-2,2-Diphenylcyclopropanecarbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development and pre-clinical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, it should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature is 2-8°C. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.