Description

6β-Hydroxy-6α,16α-Dimethylpregn-4-Ene-3,20-Dione is a high-purity synthetic steroid intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of novel therapeutic agents, particularly within the fields of endocrinology and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of advanced corticosteroid and progestogen APIs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of new steroid analogs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Employed in scaling up and optimizing synthetic routes for steroid production under cGMP conditions.
• Biochemical Research: Used as a tool compound to study steroid hormone receptors and metabolic pathways.

Basic Information

Product Name	6β-Hydroxy-6α,16α-Dimethylpregn-4-Ene-3,20-Dione
CAS No.	56630-84-3
Molecular Formula	C23H34O3
Molecular Weight	358.52 g/mol
Synonyms	6β-Hydroxy-6α,16α-dimethyl-4-pregnene-3,20-dione; 6β-Hydroxy-6α,16α-dimethylpregn-4-ene-3,20-dione; 6α,16α-Dimethyl-6β-hydroxypregn-4-ene-3,20-dione; 6β-Hydroxy-6α,16α-dimethylprogesterone; 6β-Hydroxy-6α,16α-dimethyl-δ4-pregnene-3,20-dione; 6β-Hydroxy-6α,16α-dimethyl-4-pregnene-3,20-dione (CAS 56630-84-3)
EINECS	Contact for details

Quality Control

Our 6β-Hydroxy-6α,16α-Dimethylpregn-4-Ene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.