Description

n-4-Benzoylcytidine 5-Monophosphate is a chemically modified nucleotide monophosphate, specifically a cytidine derivative protected at the N4 position with a benzoyl group. This compound is of significant value as a key synthetic intermediate and building block in oligonucleotide synthesis, particularly in the phosphoramidite method for DNA/RNA production. It is essential for researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and diagnostic reagent production, where high-purity nucleotide precursors are required.

Application

• Oligonucleotide Synthesis: A crucial phosphoramidite precursor for the solid-phase synthesis of DNA and RNA strands.
• Antisense Therapy Research: Used in the development and production of antisense oligonucleotides for therapeutic applications.
• Diagnostic Probe Manufacturing: Serves as a raw material for synthesizing labeled probes used in PCR, qPCR, and microarray technologies.
• Biochemical Research: Employed in enzymatic studies and as a substrate or intermediate in nucleotide metabolism research.
• Pharmaceutical Intermediates: Acts as a building block for novel nucleoside-based antiviral or anticancer drug candidates.
• CRISPR & Gene Editing Reagents: Used in the synthesis of guide RNAs and other nucleic acid components for gene editing tools.

Basic Information

Product Name	n-4-Benzoylcytidine 5-Monophosphate
CAS No.	56577-65-2
Molecular Formula	C17H19N3O9P
Molecular Weight	464.32 g/mol
Synonyms	4-N-Benzoylcytidine 5'-monophosphate; Cytidine, N-benzoyl-, 5'-(dihydrogen phosphate); 5'-O-Phosphono-N-benzoylcytidine; N4-Benzoylcytidine 5'-monophosphate; Bz-CMP; N-Benzoylcytidine monophosphate; 1-(5-O-Phosphono-β-D-ribofuranosyl)-4-benzamido-2(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our n-4-Benzoylcytidine 5-Monophosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the exacting standards required for sensitive biochemical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or cGMP-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or with desiccant after each use to maintain purity and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO, and alkaline solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.