Description

1-Benzofuran-5-Carbonyl Chloride is a versatile and highly reactive organic intermediate, primarily used as a key building block in advanced chemical synthesis. Its value lies in its ability to efficiently introduce the 1-benzofuran-5-carbonyl moiety into target molecules, enabling the creation of complex structures. This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for the production of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the benzofuran scaffold contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialized polymers, dyes, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a derivatization reagent or linker for labeling biomolecules and studying protein interactions.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and for constructing compound libraries for high-throughput screening.

Basic Information

Product Name	1-Benzofuran-5-Carbonyl Chloride
CAS No.	56540-70-6
Molecular Formula	C9H5ClO2
Molecular Weight	180.59 g/mol
Synonyms	5-Benzofurancarbonyl Chloride; 1-Benzofuran-5-carboxylic acid chloride; Benzofuran-5-carbonyl chloride; 5-Carboxybenzofuran chloride; 5-Benzofuroyl chloride; 5-(Chlorocarbonyl)benzofuran; 1-Oxa-2H-indene-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 1-Benzofuran-5-Carbonyl Chloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; therefore, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.