Description

1,3-Dithiolane-2-Carbonyl Chloride (9Ci) is a highly reactive organosulfur building block characterized by its dithiolane ring and acid chloride functionality. This compound matters for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on novel heterocyclic compounds, thioesters, and ligands for catalysis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing sulfur heterocycles or thioester moieties.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides where the dithiolane structure imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating chelating ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and polymers with unique properties.
• Chemical Biology Probes: Useful for modifying peptides, proteins, or other biomolecules to study biological processes.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical and custom synthesis houses serving the life sciences industry.

Basic Information

Item	Detail
Product Name	1,3-Dithiolane-2-Carbonyl Chloride (9Ci)
CAS No.	56380-59-7
Molecular Formula	C4H5ClOS2
Molecular Weight	168.66 g/mol
Synonyms	2-(Chlorocarbonyl)-1,3-dithiolane; 1,3-Dithiolane-2-carbonyl chloride; 1,3-Dithiolane-2-carboxylic acid chloride; 2-Carboxy-1,3-dithiolane chloride; 1,3-Dithiolane-2-carboxylic chloride; 2-Chlorocarbonyl-1,3-dithiolane; 1,3-Dithiolan-2-ylcarbonyl chloride
EINECS	Contact for details

Quality Control

Our 1,3-Dithiolane-2-Carbonyl Chloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.