Description

(22E)-19-Nor-5α-Cholest-22-En-3β-Ol CAS NO 56362-44-8 is a high-purity sterol derivative, specifically a 19-norcholesterol analog, valued for its role as a critical synthetic intermediate and reference standard in advanced research. Its unique structure makes it an essential building block for the synthesis of novel steroid-based compounds and for studying sterol metabolism pathways. This compound is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on developing new therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of novel steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in studies of sterol biosynthesis, metabolism, and enzyme inhibition assays.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in laboratories analyzing sterol compounds.
• Organic Synthesis: Employed as a chiral building block for constructing complex natural products and specialized molecules with sterol frameworks.
• Life Science Reagents: Incorporated into specialized kits and reagents for cell biology and metabolic pathway analysis.

Basic Information

Product Name	(22E)-19-Nor-5α-Cholest-22-En-3β-Ol
CAS No.	56362-44-8
Molecular Formula	C₂₆H₄₄O
Molecular Weight	372.64 g/mol
Synonyms	(22E)-19-Norcholest-22-en-3β-ol; 19-Nor-5α-cholest-22-en-3β-ol; 3β-Hydroxy-19-nor-5α-cholest-22-ene; 19-Norcholesterol derivative; 5α-Cholest-22-ene-3β-ol, 19-nor-; (3β)-19-Nor-5α-cholest-22-en-3-ol
EINECS	Contact for details

Quality Control

Our (22E)-19-Nor-5α-Cholest-22-En-3β-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and residual solvent analysis to ensure it meets the stringent requirements for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.