Description

(20S)-20-Methyl-13β,21-Cyclo-18-Nor-5α-Pregnan-20-Ol CAS NO 56324-74-4 is a high-purity, synthetically derived steroid derivative with a complex, modified pregnane backbone. This compound is valued for its role as a critical advanced pharmaceutical intermediate and a versatile research chemical in the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in steroid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of novel steroid-based drugs and bioactive molecules.
• Research & Development: Used as a reference standard and starting material in academic and industrial research exploring structure-activity relationships (SAR) of modified steroids.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target active pharmaceutical ingredients (APIs).
• Biochemical Research: Investigated for potential interactions with steroid hormone receptors or enzymes due to its structurally unique pregnane framework.

Basic Information

Product Name	(20S)-20-Methyl-13β,21-Cyclo-18-Nor-5α-Pregnan-20-Ol
CAS No.	56324-74-4
Molecular Formula	C22H36O
Molecular Weight	316.53 g/mol
Synonyms	20-Methyl-13β,21-cyclo-18-nor-5α-pregnan-20-ol, (20S)-form; 13β,21-Cyclo-18-nor-5α-pregnan-20-ol, 20-methyl-, (20S)-; 18-Nor-5α-pregnane-13β,21-cyclo-20-ol, 20-methyl-, (20S)-; Modified Pregnane Derivative; Steroid Intermediate 56324-74-4; 20-Methyl-13,21-cyclo-18-norpregnan-20-ol
EINECS	Contact for details

Quality Control

Our (20S)-20-Methyl-13β,21-Cyclo-18-Nor-5α-Pregnan-20-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting specifications for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.