Description

1-O,2-o-Bis(Trimethylsilyl)-3-O,5-o-Methylboranediyl-β-D-Xylofuranose is a sophisticated, organosilicon-protected carbohydrate derivative featuring a unique methylboranediyl bridge. This compound is a critical high-purity synthetic intermediate designed for advanced research and pharmaceutical development, where precise molecular architecture is paramount. It is primarily utilized by process chemists and medicinal chemists in the synthesis of nucleoside analogs, complex glycoconjugates, and other bioactive molecules requiring selective protection and functionalization strategies.

Application

• Nucleoside and Nucleotide Chemistry: Serves as a key protected intermediate in the synthesis of modified nucleosides for antiviral and anticancer drug candidates.
• Carbohydrate and Glycoconjugate Synthesis: Used in the construction of complex oligosaccharides and glycoconjugates for biological studies and therapeutic applications.
• Medicinal Chemistry & Drug Discovery: Provides a versatile building block for creating libraries of novel sugar-modified compounds for high-throughput screening.
• Process Development & Scale-up: Employed in the development of robust, scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Acts as a precursor for labeled or tagged sugar molecules used to study biological pathways and enzyme mechanisms.
• Organometallic and Catalysis Research: The boranediyl and silyl groups offer unique reactivity for exploring new catalytic transformations and metal complexation.

Basic Information

Product Name	1-O,2-o-Bis(Trimethylsilyl)-3-O,5-o-Methylboranediyl-β-D-Xylofuranose
CAS No.	56196-82-8
Molecular Formula	C15H35BO4Si2
Molecular Weight	346.42 g/mol
Synonyms	1,2-Bis-O-(trimethylsilyl)-3,5-O-methylboranediyl-β-D-xylofuranose; β-D-Xylofuranose, 1,2-bis-O-(trimethylsilyl)-3,5-O-methylboranediyl-; 1,2-Di-O-trimethylsilyl-3,5-O-methylboranediyl-β-D-xylofuranose; TMS-protected Methylboranediyl Xylofuranose; Methylboranediyl-bis(TMS)-β-D-xylofuranose; Protected Xylofuranose Boronate Ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Quality is verified through comprehensive analytical techniques including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when opening the container to prevent degradation. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.