Description

2α,21-Dihydroxypregn-4-Ene-3,20-Dione is a high-purity steroid intermediate of significant importance in advanced pharmaceutical synthesis. This compound serves as a critical building block for the development of specialized corticosteroid and other steroidal APIs, enabling precise molecular modifications. It is essential for R&D and production teams in the pharmaceutical and fine chemical industries seeking reliable, high-quality raw materials for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent corticosteroid active pharmaceutical ingredients (APIs).
• Steroid Research & Development: Used as a reference standard and starting material in medicinal chemistry for exploring new therapeutic agents.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce specific hydroxyl functionalities into the steroid backbone.
• Biochemical Studies: Utilized in metabolic pathway research and studies involving steroid hormone analogs.

Basic Information

Product Name	2α,21-Dihydroxypregn-4-Ene-3,20-Dione
CAS No.	56196-78-2
Molecular Formula	C21H30O4
Molecular Weight	346.46 g/mol
Synonyms	2α,21-Dihydroxy-4-pregnene-3,20-dione; 2α,21-Dihydroxypregn-4-ene-3,20-dione; 4-Pregnene-2α,21-diol-3,20-dione; 2α,21-Dihydroxyprogesterone; 21-Hydroxy-2α-hydroxypregn-4-ene-3,20-dione
EINECS	Contact for details

Quality Control

Our 2α,21-Dihydroxypregn-4-Ene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.