Description

3-[Bis(Trimethylsiloxy)Phosphinyl]-2-[(Trimethylsilyl)Amino]Propanoic Acid Trimethylsilyl Ester is a highly specialized organosilicon-protected amino acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to act as a protected synthon for introducing phosphinyl and amino acid functionalities under mild conditions, enabling the construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel peptide mimetics, prodrugs, and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel peptide analogs, enzyme inhibitors, and prodrug candidates.
• Agrochemical Research: Used in the development of new pesticides and herbicides with modified activity and stability profiles.
• Peptide Mimetic Synthesis: Enables the incorporation of phosphonate and silyl-protected amino acid motifs into pseudopeptide structures.
• Organocatalyst & Ligand Precursor: Serves as a starting material for creating specialized chiral ligands and catalysts for asymmetric synthesis.
• Material Science: Potential monomer or modifier for creating specialized silicon-containing polymers and hybrid materials.
• Chemical Biology Probes: Useful for synthesizing activity-based probes and labeled compounds for studying biological pathways.

Basic Information

Product Name	3-[Bis(Trimethylsiloxy)Phosphinyl]-2-[(Trimethylsilyl)Amino]Propanoic Acid Trimethylsilyl Ester
CAS No.	56196-74-8
Molecular Formula	C15H38NO5PSi4
Molecular Weight	455.78 g/mol
Synonyms	2-[(Trimethylsilyl)amino]-3-[bis(trimethylsiloxy)phosphinyl]propanoic acid trimethylsilyl ester; N-(Trimethylsilyl)-3-[bis(trimethylsiloxy)phosphinyl]alanine trimethylsilyl ester; Phosphinylalanine TMS derivative; TMS-Protected Phosphinyl Alanine Ester; 56196-74-8; Alanine derivative, N-(trimethylsilyl)-3-[bis(trimethylsiloxy)phosphinyl]-, trimethylsilyl ester
EINECS	Contact for details

Quality Control

Every batch of 3-[Bis(Trimethylsiloxy)Phosphinyl]-2-[(Trimethylsilyl)Amino]Propanoic Acid Trimethylsilyl Ester undergoes rigorous analytical testing to ensure identity, purity, and consistency suitable for research and development applications. Our quality assurance protocol includes chromatographic and spectroscopic methods to meet exacting customer requirements. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.