Description

[1R(1Alpha,4Abeta,4Balpha,10Aalpha)]-1,2,3,4,4A,4B,5,6,10,10A-Decahydro-7-Isopropyl-1,4A-Dimethylphenanthren-1-Carbonyl Chloride is a high-purity, sterically defined diterpenoid derivative, serving as a critical advanced pharmaceutical intermediate for the synthesis of complex bioactive molecules. Its precise stereochemistry makes it an invaluable building block for medicinal chemistry research and the development of novel therapeutic agents. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of steroids, terpenoids, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of steroid analogs and other complex drug candidates.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Synthesis: Building block for the production of high-value diterpenoid derivatives and natural product analogs.
• Academic Research: Employed in organic chemistry and pharmacology laboratories for studying terpenoid biosynthesis and reactivity.
• Process Development: Serves as a reference standard or starting material for scaling up synthetic routes in pilot plants.

Basic Information

Product Name	[1R(1Alpha,4Abeta,4Balpha,10Aalpha)]-1,2,3,4,4A,4B,5,6,10,10A-Decahydro-7-Isopropyl-1,4A-Dimethylphenanthren-1-Carbonyl Chloride
CAS No.	56151-64-5
Molecular Formula	C20H31ClO
Molecular Weight	322.91 g/mol
Synonyms	1-Carbonyl Chloride derivative of Abietane; (1R,4aS,4bR,10aR)-7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10a-decahydrophenanthrene-1-carbonyl chloride; Abieta-7,13-dien-18-oyl chloride (specific isomer); Diterpene acid chloride intermediate; 1R-Abietanoyl Chloride; 7-Isopropyl-1,4a-dimethyldecahydrophenanthrene-1-carbonyl chloride; 56151-64-5
EINECS	Contact for details

Quality Control

Our [1R(1Alpha,4Abeta,4Balpha,10Aalpha)]-1,2,3,4,4A,4B,5,6,10,10A-Decahydro-7-Isopropyl-1,4A-Dimethylphenanthren-1-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen) for long-term storage. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.