Description

1-Acetyl-3-(2-Aminoethyl)-1H-Indol-5-Ol Bis(Trimethylsilyl)Deriv. is a specialized, protected derivative of a key indole-based intermediate. This compound matters for its role in facilitating complex synthetic routes, particularly in pharmaceutical research and development, by offering enhanced stability and solubility for sensitive reactions. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key protected building block in the multi-step synthesis of complex drug candidates, particularly those with indole or tryptamine-based pharmacophores.
• Organic Synthesis Reagent: Used in advanced organic chemistry for introducing functionalized indole structures under mild conditions, leveraging the trimethylsilyl protecting groups.
• Biochemical Research: Serves as a precursor in the development of labeled compounds or probes for neurological and serotonin pathway studies.
• Agrochemical Synthesis: Employed in the research and development of novel pesticides or plant growth regulators that incorporate modified indole structures.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or advanced polymers requiring specific, stable heterocyclic units.

Basic Information

Product Name	1-Acetyl-3-(2-Aminoethyl)-1H-Indol-5-Ol Bis(Trimethylsilyl)Deriv.
CAS No.	56145-10-9
Molecular Formula	C19H32N2O2Si2
Molecular Weight	376.64 g/mol
Synonyms	5-Hydroxy-1-acetyl-3-(2-aminoethyl)indole Bis(trimethylsilyl) Ether; 1-Acetyl-5-(bis(trimethylsilyl)oxy)-3-(2-aminoethyl)-1H-indole; 5-(Bis(trimethylsilyl)oxy)-1-acetyl-3-(2-aminoethyl)indole; 1-Acetyl-3-(2-aminoethyl)-5-indolol Bis(trimethylsilyl) Ether; TMS Derivative of 1-Acetyl-5-hydroxy-3-(2-aminoethyl)indole; N-Acetyl-5-O-TMS-3-(2-aminoethyl)indole; Protected 5-Hydroxy-N-acetyltryptamine; 5-O-Bis-TMS-N-acetylserotonin
EINECS	Contact for details

Quality Control

Our 1-Acetyl-3-(2-Aminoethyl)-1H-Indol-5-Ol Bis(Trimethylsilyl)Deriv. is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to meet exacting R&D standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.