Description

α-(Aminomethyl)-4-Hydroxybenzenemethanol Tris(Trimethylsilyl)Deriv. is a specialized organosilicon-protected derivative of tyramine, designed for advanced synthetic applications where moisture-sensitive functional groups require protection. This compound matters as a critical building block in pharmaceutical and fine chemical synthesis, enabling complex reactions under anhydrous conditions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the production of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• As a protected synthetic intermediate in the multi-step synthesis of complex pharmaceutical molecules and bioactive compounds.
• For the development of novel drug candidates, particularly in neurological and cardiovascular research where tyramine derivatives are pharmacologically relevant.
• In peptide mimetic and combinatorial chemistry, serving as a building block with orthogonal protecting groups.
• As a key reagent in organic synthesis laboratories for introducing functionalized aromatic moieties under controlled, anhydrous conditions.
• For process chemistry and scale-up in the production of high-value fine chemicals and advanced intermediates.
• In academic and industrial research exploring new synthetic methodologies involving silyl ether protections.

Basic Information

Product Name	α-(Aminomethyl)-4-Hydroxybenzenemethanol Tris(Trimethylsilyl)Deriv.
CAS No.	56145-08-5
Molecular Formula	C16H33NO3Si3
Molecular Weight	383.70 g/mol
Synonyms	4-[(Trimethylsilyloxy)methyl]benzylamine Bis(trimethylsilyl) Ether; Tris(trimethylsilyl) Derivative of Tyramine; N-[(4-Hydroxyphenyl)methyl]methanamine Tris(trimethylsilyl) Derivative; 4-(Aminomethyl)phenol Tris-O-TMS Derivative; TMS-protected Tyramine Derivative; α-(Aminomethyl)-4-hydroxybenzyl Alcohol Tris(trimethylsilyl) Ether; Benzylamine, 4-[(trimethylsilyloxy)methyl]-, bis(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our α-(Aminomethyl)-4-Hydroxybenzenemethanol Tris(Trimethylsilyl)Deriv. is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full analytical data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.