Description

2-Amino-2-Deoxygalactose Tetrakis(Trimethylsilyl) Derivative is a key protected derivative of galactosamine, a vital amino sugar. This compound is essential for synthetic organic chemists and researchers as a versatile building block for the controlled synthesis of complex carbohydrates, glycoconjugates, and nucleoside analogs. It is primarily used in pharmaceutical R&D for drug discovery, as well as in academic research focused on glycobiology and chemical biology.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel glycosidase inhibitors, antiviral agents, and other bioactive carbohydrate-based molecules.
• Glycoconjugate Synthesis: Used for the controlled introduction of galactosamine residues into peptides, proteins, and lipids to study cell signaling and immune responses.
• Oligosaccharide Assembly: Serves as a protected glycosyl donor or acceptor in automated and solution-phase synthesis of complex oligosaccharide chains.
• Chemical Biology Probes: Employed in the development of labeled sugars and metabolic probes for imaging and studying carbohydrate metabolism in living systems.
• Nucleoside Analogue Research: Acts as a starting material for modifying nucleoside structures to explore new therapeutic avenues in oncology and virology.
• Standards & Reference Material: Provides a high-purity standard for analytical method development and quality control in carbohydrate chemistry.

Basic Information

Product Name	2-Amino-2-Deoxygalactose Tetrakis(Trimethylsilyl) Derivative
CAS No.	56145-07-4
Molecular Formula	C18H47NO5Si4
Molecular Weight	493.94 g/mol
Synonyms	Galactosamine, 2-amino-2-deoxy-, tetrakis(trimethylsilyl) derivative; N-TMS-2-Amino-2-deoxy-D-galactopyranose per-TMS derivative; 2-Amino-2-deoxy-D-galactose, TMS derivative; Per-O-trimethylsilylated D-galactosamine; 1,3,4,6-Tetra-O-trimethylsilyl-2-deoxy-2-(trimethylsilylamino)-D-galactopyranose; TMS-GalN; N,O-Per(trimethylsilyl)galactosamine
EINECS	Contact for details

Quality Control

Our 2-Amino-2-Deoxygalactose Tetrakis(Trimethylsilyl) Derivative is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.