Description

20-Hydroxy-5α-Pregnan-18-Oic Acid is a high-purity steroid derivative and a key intermediate in advanced organic synthesis. This compound matters for its role in the research and development of novel pharmaceutical agents, particularly in the exploration of neurosteroids and hormone-related pathways. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in the synthesis of specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Neurosteroid Research: Used in biochemical research to study the modulation of GABA-A receptors and other neurological targets.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical testing.
• Metabolite Studies: Employed in metabolic pathway research to understand the biotransformation of related steroid compounds.
• Fine Chemical Synthesis: A versatile precursor for the custom synthesis of complex, high-value steroid derivatives for specialized applications.

Basic Information

Product Name	20-Hydroxy-5α-Pregnan-18-Oic Acid
CAS No.	56143-33-0
Molecular Formula	C21H34O3
Molecular Weight	334.50 g/mol
Synonyms	18-Carboxy-20-hydroxy-5α-pregnan-3-one; 5α-Pregnan-18-oic acid, 20-hydroxy-; 20-Hydroxy-5α-pregnan-18-oic acid; 20-Hydroxy-5α-pregnan-18-carboxylic acid; 18-Carboxy-20-hydroxy-5α-pregnane-3-one; 5α-Pregnane-18-oic acid, 20-hydroxy-; 20-Hydroxypregnan-18-oic acid; 5α-Pregnan-20-ol-18-oic acid
EINECS	Contact for details

Quality Control

Our 20-Hydroxy-5α-Pregnan-18-Oic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.