Description

Di-tert-Butylchlorophosphate is a specialized organophosphorus reagent widely used in synthetic chemistry. Its primary value lies in its role as a phosphorylating and chlorinating agent, enabling the synthesis of complex phosphate esters and other derivatives. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of nucleotide analogs, prodrugs, and other bioactive phosphate-containing molecules.
• Agrochemical Synthesis: Used in the production of organophosphate-based pesticides and herbicides.
• Polymer Chemistry: Acts as a monomer or modifying agent in the creation of flame-retardant polymers and specialty plastics.
• Ligand and Catalyst Preparation: Employed for the synthesis of phosphine ligands and metal-organic frameworks (MOFs).
• Chemical Research: A versatile building block in academic and industrial R&D for exploring new phosphorylation methodologies.
• Surface Modification: Used to introduce phosphate groups onto material surfaces for improved adhesion or biocompatibility.

Basic Information

Product Name	Di-tert-Butylchlorophosphate
CAS No.	56119-60-9
Molecular Formula	C8H18ClO3P
Molecular Weight	228.65 g/mol
Synonyms	Chlorodi-tert-butylphosphate; Di-tert-butyl Chlorophosphate; Di-tert-butyl Phosphorochloridate; Di-tert-butylphosphonic Chloride; t-Butyl Phosphorochloridate; (t-BuO)2P(O)Cl; Phosphorochloridic Acid, Di-tert-butyl Ester; DTBCP
EINECS	Contact for details

Quality Control

Our Di-tert-Butylchlorophosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chloride Content (Titration)	Conforms
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.