Description

3α,7α,12α-Tris(Acetyloxy)Cholan-24-Oic Acid Methyl Ester is a key synthetic intermediate in the production of bile acids and their derivatives. This compound matters for its role as a versatile building block in pharmaceutical research and development, enabling the synthesis of complex steroid-based molecules. It is primarily needed by manufacturers and R&D laboratories in the pharmaceutical, fine chemical, and life science sectors for creating active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of therapeutic bile acids such as ursodeoxycholic acid (UDCA) and chenodeoxycholic acid (CDCA).
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Biochemical Research: Employed in metabolic pathway studies and as a substrate for investigating enzymes involved in steroid and bile acid metabolism.
• Fine Chemical Synthesis: Serves as a specialized building block for creating novel steroid derivatives with potential biological activity for drug discovery programs.
• Academic Research: Utilized in university and institutional labs for organic chemistry research and the development of new synthetic methodologies.

Basic Information

Product Name	3α,7α,12α-Tris(Acetyloxy)Cholan-24-Oic Acid Methyl Ester
CAS No.	56085-37-1
Molecular Formula	C₂₉H₄₆O₇
Molecular Weight	506.68 g/mol
Synonyms	Methyl 3α,7α,12α-triacetoxycholan-24-oate; Methyl 3α,7α,12α-triacetoxy-5β-cholan-24-oate; 3α,7α,12α-Triacetoxycholanic Acid Methyl Ester; Cholan-24-oic Acid, 3,7,12-tris(acetyloxy)-, Methyl Ester, (3α,5β,7α,12α)-; Methyl Triacetoxycholanate; Triacetyl Methyl Cholate; Methyl 3,7,12-Tri-O-acetylcholate
EINECS	Contact for details

Quality Control

Our 3α,7α,12α-Tris(Acetyloxy)Cholan-24-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.