Description

3-Deazaguanosine is a purine nucleoside analog, a chemically modified derivative of guanosine where a nitrogen atom in the purine ring is replaced by a carbon atom. This structural modification is significant as it alters the compound's biochemical interactions, making it a valuable tool in nucleic acid research and drug discovery. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for applications in antiviral studies, enzyme inhibition assays, and as a building block for novel therapeutic agents.

Application

• Biochemical Research: Serves as a critical reference standard and probe in studies of purine metabolism, enzyme kinetics, and nucleoside transport mechanisms.
• Antiviral Drug Development: Investigated as a potential nucleoside analog precursor for the synthesis of compounds targeting viral polymerases.
• Enzyme Inhibition Studies: Used to study the activity and specificity of enzymes like purine nucleoside phosphorylase (PNP) and adenosine deaminase.
• Pharmaceutical Intermediates: Acts as a key synthetic intermediate in the preparation of more complex nucleoside-based active pharmaceutical ingredients (APIs).
• Diagnostic Reagent Manufacturing: Employed in the formulation of specialized kits and reagents for molecular diagnostics and life science research.

Basic Information

Product Name	3-Deazaguanosine
CAS No.	56039-11-3
Molecular Formula	C10H13N5O5
Molecular Weight	283.24 g/mol
Synonyms	3-Deazaguanosine; 9-β-D-Ribofuranosyl-3-deazaguanine; 3-Carbaguanosine; 1,9-Dihydro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6H-purin-6-one; 3-Deaza-Guo; 3-Deazaguanine riboside
EINECS	Contact for details

Quality Control

Our 3-Deazaguanosine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.