Description

Guanosine-5'-Triphosphate Disodium Salt is a high-purity nucleotide essential for cellular energy transfer and signaling. This compound serves as a critical substrate for enzymatic reactions, including RNA synthesis, protein synthesis, and various kinase assays. It is indispensable for researchers and manufacturers in the biotechnology, pharmaceutical, and molecular diagnostics sectors who require reliable, high-quality biochemical reagents for their processes.

Application

• Biochemical Research: Essential substrate for in vitro transcription, translation, and enzymatic studies, including polymerase and kinase assays.
• Pharmaceutical Development: Used in drug discovery platforms, high-throughput screening (HTS), and the study of cellular signaling pathways (e.g., G-protein coupled receptors).
• Molecular Diagnostics: Key component in PCR and other nucleic acid amplification techniques as an energy source for polymerases.
• Cell Culture & Metabolism Studies: Employed in media formulations and experiments investigating cellular energy metabolism (ATP regeneration systems).
• Enzyme Manufacturing & Characterization: Used as a standard or substrate in the production and quality control of enzymes like GTPases and kinases.

Basic Information

Product Name	Guanosine-5'-Triphosphate Disodium Salt
CAS No.	56001-37-7
Molecular Formula	C10H14N5Na2O14P3
Molecular Weight	589.11 g/mol (anhydrous basis)
Synonyms	GTP Disodium Salt; Guanosine 5'-triphosphate disodium; 5'-GTP Na2; Disodium Guanosine-5'-triphosphate; Disodium 5'-GTP; Guanosine triphosphate disodium salt; Sodium Guanosine Triphosphate; 2'(3')-GTP (Disodium Salt)
EINECS	Contact for details

Quality Control

Our Guanosine-5'-Triphosphate Disodium Salt is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive biochemical applications. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Typical ≥ 98%)
pH (1% Solution)	6.0 - 8.0
Water Content (Karl Fischer)	≤ 5.0 %
Endotoxin (LAL)	< 10 EU/mg (for applicable grades)
Biological Activity	Tested in functional enzymatic assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.