Description

9-(2,3-Dihydroxypropyl)-Adenine is a modified nucleoside analog, a key building block in medicinal chemistry and biochemical research. This compound is valued for its role as a versatile intermediate in the synthesis of novel antiviral agents and nucleotide-based therapeutics. It is primarily sought by pharmaceutical R&D departments, biotechnology firms, and academic research institutions focused on developing targeted therapies and exploring nucleotide biochemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA/RNA processing.
• Pro-drug Development: Serves as a backbone for creating pro-drugs designed to improve bioavailability and targeted delivery of active pharmaceutical ingredients (APIs).
• Antiviral Agent Synthesis: Specifically utilized in research and development of adenosine-based compounds targeting viral polymerases.
• Labeled Compound Synthesis: Acts as a starting material for the preparation of isotopically labeled (e.g., C13, N15) nucleotides for metabolic tracing and diagnostic applications.

Basic Information

Product Name	9-(2,3-Dihydroxypropyl)-Adenine
CAS No.	55904-02-4
Molecular Formula	C11H15N5O2
Molecular Weight	249.27 g/mol
Synonyms	9-(2,3-Dihydroxypropyl)adenine; N9-(2,3-Dihydroxypropyl)adenine; 9-(2,3-Dihydroxypropyl)-9H-purin-6-amine; 9H-Purin-6-amine, 9-(2,3-dihydroxypropyl)-; Adenine, 9-(2,3-dihydroxypropyl)-; DHP-Ade; Ganciclovir related compound A (potential impurity)
EINECS	Contact for details

Quality Control

Our 9-(2,3-Dihydroxypropyl)-Adenine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccant use and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.