Description

3β-Hydroxy-5α-Cholestan-15-One is a high-purity steroidal ketone derivative, serving as a critical intermediate in advanced organic synthesis and pharmaceutical research. This compound is valued for its defined stereochemistry and functional groups, which make it a versatile building block for developing novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in steroid chemistry, drug discovery, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel steroid-based therapeutics and hormone analogs.
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies and enzyme inhibition assays related to cholesterol biosynthesis.
• Organic Synthesis: Serves as a sophisticated starting material for the total synthesis of complex natural products and steroidal compounds.
• Academic Research: Employed in universities and R&D labs for methodological studies in stereoselective synthesis and molecular structure-activity relationship (SAR) investigations.

Basic Information

Product Name	3β-Hydroxy-5α-Cholestan-15-One
CAS No.	55823-04-6
Molecular Formula	C27H46O2
Molecular Weight	402.66 g/mol
Synonyms	15-Keto-5α-cholestan-3β-ol; 5α-Cholestan-3β-ol-15-one; 3β-Hydroxy-5α-cholestan-15-one; (3β,5α)-Cholestane-3,15-diol-15-one; 15-Oxo-5α-cholestan-3β-ol; Steroid C15-ketone intermediate; Cholestane-3,15-dione, 3-hydroxy- (8CI)
EINECS	Contact for details

Quality Control

Our 3β-Hydroxy-5α-Cholestan-15-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets high-purity research-grade standards. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.