Description

3β,7α,17β-Tris(Trimethylsilyloxy)-5α-Androstane is a high-purity, silylated steroid derivative, a key intermediate in the synthesis of complex pharmaceutical compounds. Its value lies in providing a protected, reactive scaffold for precise chemical modifications in advanced research and development. This compound is essential for pharmaceutical chemists and research institutions engaged in the development of novel steroid-based therapeutics and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial R&D for studying steroid metabolism, receptor interactions, and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Serves as a protected precursor in multi-step organic synthesis for creating specialized and high-value chemical entities.
• Reference Standard: Can be utilized as a certified reference material (CRM) for analytical method development and quality control in steroid analysis.
• Biochemical Research: Employed in metabolic pathway studies and as a tool compound in endocrinology and biochemistry research.

Basic Information

Product Name	3β,7α,17β-Tris(Trimethylsilyloxy)-5α-Androstane
CAS No.	55801-51-9
Molecular Formula	C30H60O3Si3
Molecular Weight	553.06 g/mol
Synonyms	5α-Androstane-3β,7α,17β-triol, tris(trimethylsilyl) ether; 3β,7α,17β-Tris-O-(trimethylsilyl)-5α-androstane; Tris(trimethylsilyl) 5α-androstane-3β,7α,17β-triyl ether; Androstane-3β,7α,17β-triol TMS ether; TMS-derivatized 5α-androstanetriol
EINECS	Contact for details

Quality Control

Our 3β,7α,17β-Tris(Trimethylsilyloxy)-5α-Androstane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.