Description

7-Methyl-6-Thioguanosine is a chemically modified nucleoside analog of guanosine, featuring a methyl group at the 7-position and a sulfur atom replacing the oxygen at the 6-position. This specific modification makes it a valuable intermediate and reference standard in advanced pharmaceutical research and development, particularly for investigating nucleoside metabolism and designing novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of antiviral drugs, anticancer compounds, and biochemical probes.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel nucleoside-based antiviral and anticancer therapeutics.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies related to purine metabolism and nucleoside analog activation.
• Antiviral Drug Development: Serves as a precursor or analog in the development of compounds targeting viral polymerases.
• Life Science Reagents: Incorporated into specialized kits and reagents for molecular biology and diagnostic assay development.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and chemical biology.

Basic Information

Product Name	7-Methyl-6-Thioguanosine
CAS No.	55727-10-1
Molecular Formula	C11H15N5O4S
Molecular Weight	313.33 g/mol
Synonyms	6-Thio-7-methylguanosine; 7-Methyl-6-thioguanosine; 7-Methyl-6-mercaptoguanosine; 6-Mercapto-7-methylguanosine; 1,9-Dihydro-7-methyl-6H-purin-6-one, 2-amino-9-β-D-ribofuranosyl-; 2-Amino-7-methyl-6-thioguanosine; 7-Methyl-6-thio-Guo
EINECS	Contact for details

Quality Control

Our 7-Methyl-6-Thioguanosine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.