Description

1-β-D-Arabinofuranosyl-4-Stearoylaminopyrimidin-2(1H)-One is a specialized nucleoside analog derivative, synthesized by coupling a stearoyl moiety to the arabinofuranosylpyrimidinone core. This compound is significant for its role as a key intermediate in the research and development of novel antiviral and anticancer agents, particularly those targeting nucleic acid synthesis pathways. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on medicinal chemistry and drug discovery.

Application

• As a critical synthetic intermediate in the development of nucleoside-based antiviral drugs.
• For medicinal chemistry research exploring structure-activity relationships (SAR) of modified nucleosides.
• In the synthesis of potential anticancer prodrugs designed for targeted delivery.
• As a biochemical tool for studying enzyme inhibition, particularly polymerases and kinases.
• For the preparation of lipophilic nucleotide conjugates to enhance cellular uptake and bioavailability.
• In academic and industrial R&D programs focused on novel therapeutic modalities.

Basic Information

Product Name	1-β-D-Arabinofuranosyl-4-Stearoylaminopyrimidin-2(1H)-One
CAS No.	55726-44-8
Molecular Formula	C29H49N3O6
Molecular Weight	535.72 g/mol
Synonyms	4-Stearoylamino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone; 4-Octadecanamido-1-β-D-arabinofuranosylpyrimidin-2(1H)-one; 1-(β-D-Arabinofuranosyl)-4-stearamidopyrimidin-2(1H)-one; N4-Stearoyl-1-β-D-arabinofuranosylcytosine; Ara-C Stearoyl Amide; Lipophilic Arabinosylcytosine Derivative
EINECS	Contact for details

Quality Control

Our 1-β-D-Arabinofuranosyl-4-Stearoylaminopyrimidin-2(1H)-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.