Description

1-β-D-Arabinofuranosyl-4-Myristoylaminopyrimidin-2(1H)-One is a specialized nucleoside analogue derivative, a key intermediate in advanced pharmaceutical research and development. This compound matters for its role in the synthesis of novel antiviral and anticancer agents, offering researchers a critical building block for probing biochemical pathways and developing targeted therapies. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on nucleoside chemistry and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand mechanisms of action related to DNA/RNA synthesis.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of therapeutic agents.
• Antiviral Agent Development: Investigated for its potential activity against a range of viral pathogens due to its modified nucleoside structure.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and bioorganic chemistry.
• Process Development: Used in scaling up synthetic routes for the production of active pharmaceutical ingredients (APIs) in a GMP environment.

Basic Information

Product Name	1-β-D-Arabinofuranosyl-4-Myristoylaminopyrimidin-2(1H)-One
CAS No.	55726-43-7
Molecular Formula	C23H39N3O6
Molecular Weight	453.58 g/mol
Synonyms	4-Myristoylamino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone; 1-(β-D-Arabinofuranosyl)-4-(tetradecanoylamino)-2(1H)-pyrimidinone; N-Tetradecanoyl-1-β-D-arabinofuranosylcytosine; 4-(Tetradecanoylamino)-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone; Ara-C Myristoyl Derivative; Cytarabine Myristate Analog; L-Cytosine β-D-arabinofuranoside myristoyl derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, related substances, and residual solvents are available upon request. We adhere to stringent in-house specifications suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.