Description

1-β-D-Arabinofuranosyl-4-Lauroylaminopyrimidin-2(1H)-One is a specialized nucleoside derivative that serves as a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its role in the development of novel antiviral and anticancer agents, particularly within nucleoside analog research. It is essential for R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors seeking to innovate in targeted therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used in academic and industrial R&D for studying enzyme mechanisms, nucleotide metabolism, and structure-activity relationships (SAR).
• Antiviral Agent Development: Serves as a precursor for compounds targeting viral polymerases and reverse transcriptases.
• Oncology Research: Investigated for its potential incorporation into prodrugs designed to selectively target cancer cells.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	1-β-D-Arabinofuranosyl-4-Lauroylaminopyrimidin-2(1H)-One
CAS No.	55726-42-6
Molecular Formula	C21H35N3O6
Molecular Weight	425.52 g/mol
Synonyms	4-Lauroylamino-1-β-D-arabinofuranosylpyrimidin-2(1H)-one; 1-β-D-Arabinofuranosyl-4-dodecanamido-2-pyrimidinone; N-Dodecanoylcytosine β-D-arabinofuranoside; Lauroyl Ara-C; 4-(Dodecanoylamino)-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
EINECS	Contact for details

Quality Control

Our 1-β-D-Arabinofuranosyl-4-Lauroylaminopyrimidin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.