Description

1-β-D-Arabinofuranosyl-4-Decanoylaminopyrimidin-2(1H)-One is a specialized nucleoside analog with a decanoyl side chain, representing a key intermediate in advanced pharmaceutical synthesis. This compound is critical for researchers and manufacturers developing novel antiviral and anticancer therapeutics, where precise molecular structure is paramount for biological activity. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical producers, and academic institutions engaged in nucleoside chemistry and prodrug development.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Prodrug Development: Used in research to create lipophilic prodrugs, enhancing the bioavailability and cellular uptake of active pharmaceutical ingredients (APIs).
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies related to nucleic acid metabolism and polymerase function.
• Antiviral Agent Synthesis: A key precursor in the development of compounds targeting viral replication mechanisms.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the therapeutic profile of nucleoside analogs.
• Fine Chemical Production: Used in custom synthesis and contract manufacturing of high-value, complex organic molecules.

Basic Information

Product Name	1-β-D-Arabinofuranosyl-4-Decanoylaminopyrimidin-2(1H)-One
CAS No.	55726-41-5
Molecular Formula	C₁₉H₃₁N₃O₆
Molecular Weight	397.47 g/mol
Synonyms	4-Decanoylamino-1-β-D-arabinofuranosylpyrimidin-2(1H)-one; 1-(β-D-Arabinofuranosyl)-4-decanoylaminopyrimidin-2(1H)-one; N-Decanoyl-ara-cytidine; Ara-C Decanoate; Cytarabine Decanoate Derivative; 4-(Decanoylamino)-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone; 1-β-D-Arabinofuranosyl-4-decanoylamino-2-pyrimidinone
EINECS	Contact for details

Quality Control

Our 1-β-D-Arabinofuranosyl-4-Decanoylaminopyrimidin-2(1H)-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.