Description

2-Azido-2-Deoxy-3-O,4-o-Dibenzyl-6-o-Acetyl-α-D-Glucopyranosyl Bromide is a sophisticated, protected glycosyl bromide derivative, serving as a critical synthetic intermediate in advanced carbohydrate chemistry. Its primary value lies in enabling the stereoselective construction of complex oligosaccharides and glycoconjugates, which are essential for pharmaceutical and biochemical research. This high-purity building block is indispensable for researchers and process chemists in the pharmaceutical, biotechnology, and academic sectors who are developing novel therapeutics, vaccines, and diagnostic tools.

Application

• Glycosylation Reagent: A key electrophile for the stereoselective synthesis of 2-azido-2-deoxy glycosidic linkages, crucial for assembling oligosaccharides and glycoconjugates.
• Pharmaceutical Intermediate: Used in the research and development of antibiotic derivatives, antiviral agents, and other bioactive molecules that target carbohydrate-processing enzymes.
• Glycobiology Research: Essential for constructing defined glycan structures to study protein-carbohydrate interactions, cell signaling, and immune response mechanisms.
• Carbohydrate Mimetic Synthesis: Serves as a precursor for creating glycomimetics and neoglycoconjugates with potential therapeutic applications.
• Process Chemistry: Employed in scale-up synthesis for the production of carbohydrate-based active pharmaceutical ingredients (APIs) under controlled GMP-like conditions.
• Chemical Biology Probes: Used to synthesize tagged or labeled glycans for imaging, diagnostic assays, and target identification studies.

Basic Information

Product Name	2-Azido-2-Deoxy-3-O,4-o-Dibenzyl-6-o-Acetyl-α-D-Glucopyranosyl Bromide
CAS No.	55682-50-3
Molecular Formula	C22H24BrN3O5
Molecular Weight	490.35 g/mol
Synonyms	2-Azido-3,4-di-O-benzyl-6-O-acetyl-2-deoxy-α-D-glucopyranosyl bromide; 2-Azido-2-deoxy-3,4-di-O-benzyl-6-O-acetyl-α-D-glucopyranosyl bromide; 3,4-Di-O-benzyl-6-O-acetyl-2-deoxy-2-azido-α-D-glucopyranosyl bromide; α-D-Glucopyranosyl bromide, 2-azido-2-deoxy-3,4-di-O-benzyl-6-O-acetyl-; Glycosyl Bromide Derivative; Protected Glucosyl Azide Bromide; 2-Azido-2-deoxyglucose derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Azido-2-Deoxy-3-O,4-o-Dibenzyl-6-o-Acetyl-α-D-Glucopyranosyl Bromide is manufactured and tested under strict quality management systems to ensure consistency and reliability for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profile. Our quality commitment aligns with the standards required for research and development use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a freezer. This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opened to prevent decomposition. Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.