Description

1,4-Dihydro-4-Oxo-1-(Trimethylsilyl)-2-[Bis(Trimethylsilyl)Amino]-6-Pteridinecarboxylic Acid Trimethylsilyl Ester is a highly functionalized pteridine derivative featuring multiple trimethylsilyl (TMS) protecting groups. This compound is a critical synthetic intermediate for the preparation of complex heterocyclic systems, particularly in advanced pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel pteridine-based drug candidates, including potential kinase inhibitors and antifolate agents.
• Agrochemical Research: Used in the development of new herbicides and plant growth regulators that target specific enzymatic pathways.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex, multi-functional heterocyclic compounds in custom synthesis projects.
• Material Science Research: Potential precursor for organic electronic materials due to its conjugated pteridine core and silyl-protected functionalities.
• Biochemical Probe Development: Can be used to create labeled or modified pteridine analogs for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	1,4-Dihydro-4-Oxo-1-(Trimethylsilyl)-2-[Bis(Trimethylsilyl)Amino]-6-Pteridinecarboxylic Acid Trimethylsilyl Ester
CAS No.	55649-41-7
Molecular Formula	C₂₀H₃₉N₅O₃Si₄
Molecular Weight	526.92 g/mol
Synonyms	6-Pteridinecarboxylic acid, 1,4-dihydro-4-oxo-1-(trimethylsilyl)-2-[bis(trimethylsilyl)amino]-, trimethylsilyl ester; 2-[Bis(trimethylsilyl)amino]-1,4-dihydro-4-oxo-1-(trimethylsilyl)-6-pteridinecarboxylic acid trimethylsilyl ester; TMS-protected pteridine carboxylic acid ester; Per-silylated pteridine intermediate
EINECS	Contact for details

Quality Control

Our 1,4-Dihydro-4-Oxo-1-(Trimethylsilyl)-2-[Bis(Trimethylsilyl)Amino]-6-Pteridinecarboxylic Acid Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment, and consideration should be given to handling under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.