Description

Endo-Tropacocaine (8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl) Benzoate Hcl is a high-purity synthetic organic compound belonging to the tropane alkaloid class, specifically formulated as a hydrochloride salt for enhanced stability and handling. This compound is of significant interest in advanced chemical research and development due to its complex bicyclic structure, which serves as a critical scaffold for pharmacological studies. It is primarily utilized by research institutions, pharmaceutical development laboratories, and specialty chemical manufacturers focusing on neuroscience, receptor binding studies, and the synthesis of novel chemical entities.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel tropane-based compounds for potential therapeutic applications.
• Neuroscientific Studies: Used in academic and industrial research to investigate neurotransmitter systems, particularly those involving monoamine transporters, due to its structural similarity to cocaine.
• Chemical Synthesis: Acts as a sophisticated building block for organic chemists developing new molecules with complex polycyclic architectures.
• Analytical Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control testing, ensuring accurate identification and quantification in various matrices.
• Biochemical Assays: Utilized in vitro to study protein-ligand interactions, enzyme inhibition, and other biochemical pathways relevant to medicinal chemistry.

Basic Information

Item	Details
Product Name	Endo-Tropacocaine (8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl) Benzoate Hcl
CAS No.	55623-27-3
Molecular Formula	C16H21NO2·HCl
Molecular Weight	295.80 g/mol
Synonyms	Endo-Tropacocaine Hydrochloride; 3β-Benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane Hydrochloride; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl benzoate hydrochloride; Tropacocaine HCl (endo- isomer); Pseudotropine benzoate hydrochloride; Benzoic acid, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrochloride; Contact for details for additional synonyms.
EINECS	Contact for details

Quality Control

Our Endo-Tropacocaine Hcl is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and specific tests for related substances and residual solvents. We provide a Certificate of Analysis (COA) with each shipment, detailing all test results against predefined specifications to ensure consistency and traceability for research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.