Description

3-(Trimethylsiloxy)Butanoic Acid Methyl Ester is a versatile organosilicon compound, a silyl ester of a β-keto acid derivative, valued for its role as a key synthetic intermediate and protecting group reagent. Its primary commercial importance lies in enabling complex organic syntheses, particularly in the pharmaceutical and fine chemical sectors, where precise molecular construction is critical. This product is essential for R&D chemists and production specialists in industries focused on developing active pharmaceutical ingredients (APIs), advanced agrochemicals, and specialty performance materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Silicon-Based Protecting Group: Used to protect reactive carbonyl or hydroxyl functionalities during sensitive synthetic sequences, improving reaction selectivity and yield.
• Agrochemical Synthesis: Serves as a precursor in the manufacturing of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the synthesis of flavors, fragrances, and other high-value specialty chemicals.
• Polymer & Material Science: Acts as a modifier or cross-linking agent in the development of silicone-based polymers and advanced material coatings.
• Laboratory Reagent: Used in academic and industrial research for methodological development and exploratory chemistry.

Basic Information

Product Name	3-(Trimethylsiloxy)Butanoic Acid Methyl Ester
CAS No.	55590-74-4
Molecular Formula	C8H18O3Si
Molecular Weight	190.31 g/mol
Synonyms	Methyl 3-(trimethylsiloxy)butanoate; 3-(Trimethylsilyloxy)butyric Acid Methyl Ester; Butanoic acid, 3-(trimethylsiloxy)-, methyl ester; Methyl 3-(trimethylsilyloxy)butyrate; TMS enol ether of methyl acetoacetate; Trimethylsilyl methyl acetoacetate; Methyl 3-oxobutanoate trimethylsilyl enol ether
EINECS	Contact for details

Quality Control

Our 3-(Trimethylsiloxy)Butanoic Acid Methyl Ester is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.410 - 1.420
Density (g/mL at 20°C)	0.92 - 0.96

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.