Description

2-(Trimethylsiloxy)Butanedioic Acid Dimethyl Ester is a versatile organosilicon-protected derivative of succinic acid, offering unique reactivity for advanced synthetic transformations. This compound is valued for its role as a key protected intermediate, enabling precise chemical modifications in sensitive environments. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protected dicarboxylic acid functionalities.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides where controlled release of the acid moiety is required.
• Peptide Chemistry: Serves as a protected aspartic acid or glutamic acid analog in solid-phase peptide synthesis (SPPS) and peptide coupling reactions.
• Polymer Modification: Acts as a functional monomer or cross-linking agent in the production of specialty polymers with tailored properties.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions and nucleophilic substitutions where the silyloxy group acts as a protecting and directing group.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing specific esters and lactones used in creating complex aroma profiles.

Basic Information

Product Name	2-(Trimethylsiloxy)Butanedioic Acid Dimethyl Ester
CAS No.	55590-73-3
Molecular Formula	C9H18O5Si
Molecular Weight	234.32 g/mol
Synonyms	Dimethyl 2-(Trimethylsiloxy)Succinate; Succinic Acid, 2-(Trimethylsiloxy)-, Dimethyl Ester; 2-(Trimethylsilyloxy)succinic Acid Dimethyl Ester; 2-(TMSoxy)succinic Acid Dimethyl Ester; NSC 334058; Dimethyl O-Trimethylsilylsuccinate; 2-Hydroxysuccinic Acid Dimethyl Ester Trimethylsilyl Ether
EINECS	Contact for details

Quality Control

Our 2-(Trimethylsiloxy)Butanedioic Acid Dimethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.