Description

2-Methylbenzoic Acid Trimethylsilyl Ester is a versatile organosilicon derivative of o-toluic acid, primarily utilized as a key protected intermediate in advanced organic synthesis. Its value lies in the trimethylsilyl (TMS) group, which acts as a robust protecting group for carboxylic acids, enhancing solubility and altering reactivity for selective transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require high-purity intermediates for complex multi-step syntheses.

Application

• Pharmaceutical Intermediate: Serves as a protected carboxylic acid building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the TMS ester functionality is crucial for specific reaction steps.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the 2-methylbenzoate moiety under mild conditions, often used in peptide coupling and esterification reactions.
• Material Science Precursor: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials requiring tailored aromatic esters.
• Analytical Chemistry: Utilized as a derivatization agent in gas chromatography (GC) and mass spectrometry (MS) for the analysis of carboxylic acids.
• Flavor & Fragrance Industry: Functions as an intermediate for synthesizing specific aromatic esters used in high-value fragrance compositions.

Basic Information

Item	Details
Product Name	2-Methylbenzoic Acid Trimethylsilyl Ester
CAS No.	55557-15-8
Molecular Formula	C11H16O2Si
Molecular Weight	208.33 g/mol
Synonyms	o-Toluic Acid Trimethylsilyl Ester; 2-Methylbenzoic Acid TMS Ester; Trimethylsilyl 2-Methylbenzoate; (2-Methylphenyl)carboxylic Acid Trimethylsilyl Ester; TMS-o-Toluate; Benzoic Acid, 2-Methyl-, Trimethylsilyl Ester; CAS 55557-15-8
EINECS	Contact for details

Quality Control

Our 2-Methylbenzoic Acid Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.