Description

3-Methyldigitoxigenin is a specialized cardiac glycoside derivative, a methylated analog of digitoxigenin. This compound is a crucial intermediate and reference standard in the research and development of cardiotonic agents and other pharmaceutical products. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of novel therapeutic compounds. Its defined structure makes it valuable for analytical and synthetic applications.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in the production of cardiac drugs.
• Biochemical Research: Serves as a key intermediate or tool compound in studies investigating the structure-activity relationships (SAR) of cardiac glycosides.
• Active Pharmaceutical Ingredient (API) Synthesis: Acts as a critical building block in the multi-step synthesis of novel or generic cardiotonic medications.
• Metabolite Studies: Employed in pharmacological and toxicological research to study the metabolism and biological pathways of related digitoxin compounds.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and cardiovascular pharmacology.

Basic Information

Product Name	3-Methyldigitoxigenin
CAS No.	55547-62-1
Molecular Formula	C₂₄H₃₄O₅
Molecular Weight	402.53 g/mol
Synonyms	3-Methyldigitoxigenin; Digitoxigenin, 3-methyl-; 3-Methyl-digitoxigenin; 3-O-Methyldigitoxigenin; (3β,5β)-3-Methoxy-14-hydroxycard-20(22)-enolide; 14-Hydroxy-3-methoxy-5β-card-20(22)-enolide
EINECS	Contact for details

Quality Control

Our 3-Methyldigitoxigenin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, detailing all test results against established internal specifications. Our commitment ensures material consistency suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.