Description

2-Methyl-3-[(Trimethylsilyl)Oxy]Propionic Acid Trimethylsilyl Ester is a specialized organosilicon compound featuring dual trimethylsilyl (TMS) protecting groups. This chemical is a critical reagent in advanced organic synthesis, valued for its role in protecting carboxylic acid and hydroxyl functionalities simultaneously, thereby enabling complex multi-step reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate Synthesis: Serves as a key building block and protecting group agent in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Employed in the development and production of novel pesticides, herbicides, and plant growth regulators requiring sophisticated synthetic pathways.
• Advanced Material Precursor: Used in the synthesis of specialty polymers, silicone-based materials, and other functional materials where precise molecular architecture is required.
• Peptide and Natural Product Chemistry: Facilitates the synthesis of sensitive peptide fragments and complex natural product analogs by protecting reactive carboxyl and alcohol groups.
• Process Chemistry & Scale-Up: Applied in process optimization and pilot-scale production where reliable protection/deprotection strategies are essential for yield and purity.
• Academic & Industrial R&D: A valuable tool in research laboratories for methodological development and exploring new chemical spaces in organic synthesis.

Basic Information

Product Name	2-Methyl-3-[(Trimethylsilyl)Oxy]Propionic Acid Trimethylsilyl Ester
CAS No.	55530-42-2
Molecular Formula	C10H24O3Si2
Molecular Weight	248.47 g/mol
Synonyms	2-Methyl-3-(trimethylsiloxy)propionic acid trimethylsilyl ester; 3-(Trimethylsiloxy)-2-methylpropanoic acid trimethylsilyl ester; Bis(trimethylsilyl) 2-methyl-3-(trimethylsiloxy)propionate; TMS ester of 2-methyl-3-(trimethylsiloxy)propionic acid; 2-Methyl-3-trimethylsilyloxypropionic acid TMS ester; Propanoic acid, 2-methyl-3-[(trimethylsilyl)oxy]-, trimethylsilyl ester
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-[(Trimethylsilyl)Oxy]Propionic Acid Trimethylsilyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive analytical data, including HPLC/GC purity and identity confirmation (IR, NMR). Certificates of Analysis (COA) detailing all specifications are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.