Description

n-Acetylglucosylamine Tetra-Tms is a key protected monosaccharide derivative, specifically the pertrimethylsilylated form of N-acetylglucosamine. This compound is essential as a versatile synthetic intermediate and analytical standard in advanced carbohydrate chemistry and life science research. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications such as glycosylation studies, oligosaccharide synthesis, and mass spectrometry calibration.

Application

• Glycosylation Reagent: A crucial building block for the synthesis of complex oligosaccharides and glycoconjugates in medicinal chemistry.
• Analytical Standard: Used as a reference standard in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for the analysis of carbohydrate derivatives.
• Biochemical Research: Serves as a protected intermediate in studies of enzymatic pathways involving N-acetylglucosamine, such as chitin metabolism and glycosaminoglycan biosynthesis.
• Pharmaceutical Development: Employed in the research and development of glycosidase inhibitors, anti-inflammatory agents, and other therapeutics targeting carbohydrate-mediated processes.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of labeled compounds, specialty surfactants, and advanced materials.

Basic Information

Product Name	n-Acetylglucosylamine Tetra-Tms
CAS No.	55529-74-3
Molecular Formula	C20H49NO5Si4
Molecular Weight	520.0 g/mol (approx.)
Synonyms	N-Acetylglucosamine, per-O-trimethylsilyl; 2-Acetamido-2-deoxy-D-glucopyranose, per-O-TMS; 2-Acetamido-1,3,4,6-tetra-O-trimethylsilyl-2-deoxy-D-glucopyranose; GlcNAc tetra-TMS; N-Acetyl-D-glucosamine tetra(trimethylsilyl) ether; 1,3,4,6-Tetra-O-trimethylsilyl-N-acetyl-D-glucosamine; D-Glucose, 2-(acetylamino)-2-deoxy-, 1,3,4,6-tetrakis-O-(trimethylsilyl)-
EINECS	Contact for details

Quality Control

Our n-Acetylglucosylamine Tetra-Tms is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment (HPLC, GC) and structural confirmation (NMR, IR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture absorption and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Purity (GC or HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.