Description

5,2'-o-Dimethyluridine is a specifically modified nucleoside derivative, playing a crucial role in advanced biochemical research and pharmaceutical development. Its dimethylated structure makes it a valuable building block for studying RNA structure, function, and for the synthesis of novel oligonucleotide analogs. This compound is essential for researchers and manufacturers in the fields of nucleoside chemistry, antiviral drug discovery, and molecular biology, where precise chemical modifications are required to probe biological mechanisms or develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a modified building block in oligonucleotide synthesis to study RNA structure, stability, and protein-RNA interactions.
• Proteomics & Genomics: Serves as a tool compound in metabolic pathway studies and for investigating enzyme mechanisms involving nucleotide substrates.
• Diagnostic Reagent Development: Potential use in the creation of labeled probes or standards for diagnostic assays.
• Academic & Industrial R&D: Fundamental research reagent in universities and corporate labs focused on nucleic acid chemistry and drug discovery.

Basic Information

Product Name	5,2'-o-Dimethyluridine
CAS No.	55486-09-4
Molecular Formula	C11H16N2O6
Molecular Weight	272.25 g/mol
Synonyms	2'-O-Methyl-5-methyluridine; 5,2'-Di-O-methyluridine; 1-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione; 5-Methyl-2'-O-methyluridine; Uridine, 5,2'-di-O-methyl-
EINECS	Contact for details

Quality Control

Our 5,2'-o-Dimethyluridine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our commitment ensures the high purity, consistency, and traceability required for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.