Description

12α-Hydroxy-3α-(3-Methoxy-1,3-Dioxopropoxy)-24-Methylene-5α-Lanost-8-En-26-Oic Acid Methyl Ester is a high-purity, semi-synthetic lanostane derivative with significant potential in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel therapeutic agents, particularly in the exploration of anti-inflammatory and metabolic pathways. It is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing next-generation steroid-based treatments.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel lanostane-based drug candidates targeting inflammation and metabolic disorders.
• Biochemical Research: Used in academic and industrial laboratories to study enzyme inhibition, receptor binding, and metabolic pathways involving sterol biosynthesis.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis using HPLC or LC-MS.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex natural product derivatives and active pharmaceutical ingredients (APIs).
• Drug Discovery: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.

Basic Information

Product Name	12α-Hydroxy-3α-(3-Methoxy-1,3-Dioxopropoxy)-24-Methylene-5α-Lanost-8-En-26-Oic Acid Methyl Ester
CAS No.	55450-36-7
Molecular Formula	C36H56O7
Molecular Weight	600.83 g/mol
Synonyms	Methyl 12α-Hydroxy-3α-(3-methoxy-1,3-dioxopropoxy)-24-methylene-5α-lanost-8-en-26-oate; 24-Methylene-5α-lanost-8-ene-26-oic acid, 12α-hydroxy-3α-(3-methoxy-1,3-dioxopropoxy)-, methyl ester; Lanostane derivative 55450-36-7; 12α-Acetoxy-3α-(3-methoxy-1,3-dioxopropoxy)-24-methylene-5α-lanost-8-en-26-oic acid methyl ester (related); 3α-(Methoxycarbonyl)propionyloxy-12α-hydroxy-24-methylene-5α-lanost-8-en-26-oic acid methyl ester
EINECS	Contact for details

Quality Control

Our 12α-Hydroxy-3α-(3-Methoxy-1,3-Dioxopropoxy)-24-Methylene-5α-Lanost-8-En-26-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.