Description

(25S)-5α-Spirostane-2α,3β,27-Triol Triacetate is a high-purity, semi-synthetic steroidal derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in its defined stereochemistry and functionalization, which provides a versatile scaffold for synthesizing novel steroid-based therapeutic agents. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on developing new drugs, particularly in areas like hormone therapy, anti-inflammatory agents, and metabolic regulators.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic candidates.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical laboratories.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex steroidal molecules.
• Biochemical Research: Utilized as a tool compound to study steroid receptor interactions and metabolic pathways.

Basic Information

Product Name	(25S)-5α-Spirostane-2α,3β,27-Triol Triacetate
CAS No.	55429-17-9
Molecular Formula	C33H50O8
Molecular Weight	574.75 g/mol
Synonyms	(25S)-Spirostane-2α,3β,27-triol 2,3,27-triacetate; 2α,3β,27-Triacetoxy-(25S)-5α-spirostane; (25S)-5α-Spirostane-2α,3β,27-triol 2,3,27-triacetate; Tigogenin 2α,3β,27-triol triacetate (25S-isomer); 27-Acetoxytigogenin 2,3-diacetate; (25S)-2α,3β,27-Trihydroxy-5α-spirostan 2,3,27-triacetate
EINECS	Contact for details

Quality Control

Our (25S)-5α-Spirostane-2α,3β,27-Triol Triacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.