Description

(2-Amino-3-Trifluoromethyl-Phenyl)-Methanol is a versatile trifluoromethylated aniline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the amino and trifluoromethyl groups on the aromatic ring, which are pivotal for modulating the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced potency and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) drugs and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of modern herbicides and fungicides, where the CF₃ group improves lipophilicity and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, contributing to the molecular design of charge-transport layers and emissive compounds.
• Complex Ligand & Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis and material science applications.
• Fluorinated Dye & Pigment Research: Acts as a starting material for synthesizing specialized fluorinated dyes with unique optical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for bespoke synthesis projects requiring high-purity, functionalized aromatic compounds.

Basic Information

Product Name	(2-Amino-3-Trifluoromethyl-Phenyl)-Methanol
CAS No.	55414-60-3
Molecular Formula	C₈H₈F₃NO
Molecular Weight	191.15 g/mol
Synonyms	2-Amino-α-(trifluoromethyl)benzenemethanol; 1-(2-Amino-3-(trifluoromethyl)phenyl)methanol; 2-Amino-3-(trifluoromethyl)benzyl alcohol; (2-Amino-3-trifluoromethylphenyl)methanol; α-(Trifluoromethyl)-2-aminobenzyl alcohol; Benzenemethanol, 2-amino-α-(trifluoromethyl)-; 3-(Trifluoromethyl)anthranilyl alcohol
EINECS	Contact for details

Quality Control

Every batch of (2-Amino-3-Trifluoromethyl-Phenyl)-Methanol is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available upon request, providing full traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.