Description

7α,17β-Dihydroxy-5β-Androstan-3-One is a high-purity steroid derivative, also known as 5β-Dihydrotestosterone, serving as a critical intermediate in advanced pharmaceutical synthesis. Its precise stereochemistry makes it a valuable building block for developing therapeutic agents targeting hormonal pathways and metabolic disorders. This compound is essential for research and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors requiring reliable, high-quality steroid precursors.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in metabolic studies, enzyme inhibition assays, and receptor binding research.
• Hormone Analog Development: Serves as a core structure for creating novel androgen receptor modulators and other endocrine-targeting compounds.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the 5β-androstane skeleton into complex molecules.
• Metabolite Standard: Utilized in analytical laboratories for the calibration and validation of LC-MS/MS and HPLC methods in clinical and forensic toxicology.

Basic Information

Product Name	7α,17β-Dihydroxy-5β-Androstan-3-One
CAS No.	55365-27-0
Molecular Formula	C19H30O3
Molecular Weight	306.44 g/mol
Synonyms	5β-Dihydrotestosterone; 5β-Androstane-3-one-7α,17β-diol; 7α,17β-Dihydroxy-5β-androstan-3-one; 5β-DHT; 5β-Androstanediol-3-one; 3-Oxo-5β-androstane-7α,17β-diol; NSC 113986
EINECS	Contact for details

Quality Control

Our 7α,17β-Dihydroxy-5β-Androstan-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.