Description

3α-Trimethylsilyloxy-5β-Cholestane is a high-purity, steroidal derivative characterized by its specific trimethylsilyl (TMS) ether functional group. This compound serves as a critical intermediate or reference standard in advanced organic synthesis and analytical research, particularly in the fields of steroid chemistry and metabolic studies. It is primarily utilized by pharmaceutical R&D laboratories, analytical testing facilities, and specialty chemical manufacturers requiring precise molecular structures for method development and synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex steroidal drugs and bioactive molecules.
• Analytical Reference Standard: Used for method development, calibration, and quantification in chromatographic analyses (e.g., GC, HPLC) for steroid profiling.
• Metabolic Research: Serves as a derivative or internal standard in studies investigating cholesterol metabolism and related biochemical pathways.
• Chemical Synthesis: Employed in organic chemistry research for the preparation of novel steroidal compounds with modified properties.
• Quality Control: Acts as a certified standard for the purity testing of steroidal raw materials and finished products in GMP environments.

Basic Information

Product Name	3α-Trimethylsilyloxy-5β-Cholestane
CAS No.	55331-93-6
Molecular Formula	C₃₀H₅₄OSi
Molecular Weight	458.84 g/mol
Synonyms	5β-Cholestan-3α-ol trimethylsilyl ether; 3α-Trimethylsiloxy-5β-cholestane; Cholestane-3α-ol, TMS ether; 5β-Cholestan-3α-yloxy-trimethylsilane; (3α,5β)-Cholestan-3-ol trimethylsilyl ether; TMS ether of 5β-cholestan-3α-ol
EINECS	Contact for details

Quality Control

Our 3α-Trimethylsilyloxy-5β-Cholestane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards, and specifications can be tailored to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.