Description

Impromidine is a potent and highly selective histamine H2-receptor agonist, widely recognized for its use as a pharmacological research tool. Its primary value lies in its ability to stimulate gastric acid secretion, making it a critical compound for studying receptor mechanisms and gastrointestinal physiology. This product is essential for pharmaceutical R&D laboratories, academic research institutions, and chemical suppliers serving the life sciences sector. Impromidine CAS NO 55273-05-7 is supplied to support high-purity biochemical and pharmacological investigations.

Application

• Pharmacological Research: A standard tool compound for studying histamine H2-receptor function, activation, and signaling pathways in vitro and in vivo.
• Gastrointestinal Physiology Studies: Used to stimulate gastric acid secretion in experimental models to understand regulatory mechanisms and evaluate potential therapeutics.
• Receptor Binding Assays: Serves as a high-affinity ligand in competitive binding studies to characterize H2-receptor density and antagonist interactions.
• Biochemical Standard: Employed as a reference standard in analytical method development and validation for quality control in related pharmaceutical synthesis.
• Academic & Educational Use: Utilized in university laboratories for teaching advanced concepts in receptor pharmacology and medicinal chemistry.
• Drug Discovery Screening: Acts as a positive control in high-throughput screening (HTS) campaigns targeting the H2-receptor for new drug candidates.

Basic Information

Product Name	Impromidine
CAS No.	55273-05-7
Molecular Formula	C20H28N8
Molecular Weight	380.50 g/mol
Synonyms	N-[3-(1H-Imidazol-4-yl)propyl]-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine; SK&F 92676; Impromidine Hydrochloride (common salt form); Histamine H2-receptor agonist; H2 agonist
EINECS	Contact for details

Quality Control

Our Impromidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.