Description

11-β-Hydroxypregnanedione is a high-purity steroid intermediate of significant importance in pharmaceutical synthesis. This compound serves as a critical building block for the development of advanced steroid-based therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the production of corticosteroids and other specialized hormonal agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent corticosteroid APIs (Active Pharmaceutical Ingredients).
• Steroid Research: Used in biochemical and pharmacological research to study steroid metabolism, receptor binding, and enzyme inhibition.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical laboratories.
• Process Development: Employed in scaling up and optimizing synthetic routes for novel steroid derivatives in pilot and commercial manufacturing.

Basic Information

Product Name	11-β-Hydroxypregnanedione
CAS No.	55176-88-0
Molecular Formula	C21H30O3
Molecular Weight	330.46 g/mol
Synonyms	11β-Hydroxypregnane-3,20-dione; 11β-Hydroxy-5β-pregnane-3,20-dione; 11β-Hydroxy-5β-pregnanedione; 11β-Hydroxypregnanedione; 11β-OH-Pregnanedione; 5β-Pregnane-3,20-dione, 11β-hydroxy-; 11β-Hydroxy-5β-pregnane-3,20-dione
EINECS	Contact for details

Quality Control

Our 11-β-Hydroxypregnanedione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications for pharmaceutical-grade intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a dry environment and opened under controlled conditions to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.