Description

2-Bromo-4,5-Dimethoxybenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its ability to efficiently introduce the 2-bromo-4,5-dimethoxybenzoyl moiety into target molecules, enabling the construction of complex pharmacophores and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where the dimethoxybenzene scaffold is required.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with specific electronic or optical properties.
• Peptide Mimetics and Bioconjugation: The reactive acid chloride group facilitates coupling reactions to create peptide analogs or for labeling biomolecules.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D.

Basic Information

Product Name	2-Bromo-4,5-Dimethoxybenzoyl Chloride
CAS No.	55171-61-4
Molecular Formula	C9H8BrClO3
Molecular Weight	279.51 g/mol
Synonyms	4,5-Dimethoxy-2-bromobenzoyl chloride; 2-Bromo-4,5-dimethoxybenzoic acid chloride; (2-Bromo-4,5-dimethoxyphenyl)carbonyl chloride; 2-Bromo-4,5-dimethoxybenzene-1-carbonyl chloride; Benzoic acid, 2-bromo-4,5-dimethoxy-, chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4,5-Dimethoxybenzoyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.