Description

[2-(Acetylamino)Ethyl]Phosphonic Acid Bis(Trimethylsilyl) Ester CAS NO 55108-88-8 is a key organosilicon-protected phosphonic acid derivative, serving as a versatile synthetic intermediate and protecting group reagent. Its primary value lies in enabling complex organic synthesis, particularly in the preparation of bioactive molecules and functional materials, by safeguarding reactive phosphonic acid functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, specialized building blocks for their development pipelines.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those containing phosphonate or bisphosphonate groups for therapeutic applications.
• Agrochemical Synthesis: Serves as a protected precursor for creating herbicides, plant growth regulators, and other crop protection agents with phosphonic acid moieties.
• Ligand and Catalyst Preparation: Employed in the development of specialized ligands for metal catalysis and in the creation of organocatalysts.
• Surface Modification Agent: Utilized to functionalize material surfaces (e.g., silica, metals) with stable phosphonate layers for improved adhesion, corrosion resistance, or biocompatibility.
• Peptide and Nucleotide Analog Synthesis: Acts as a key building block for incorporating phosphonate isosteres into peptides and nucleotide analogs, which are valuable in medicinal chemistry.
• Polymer Chemistry: Used as a monomer or modifier in the synthesis of specialty polymers, including flame retardants and ion-exchange resins.

Basic Information

Product Name	[2-(Acetylamino)Ethyl]Phosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	55108-88-8
Molecular Formula	C10H26NO4PSi2
Molecular Weight	311.46 g/mol
Synonyms	N-Acetyl-2-aminoethylphosphonic Acid Bis(trimethylsilyl) Ester; Phosphonic Acid, P-[2-(acetylamino)ethyl]-, bis(trimethylsilyl) ester; (2-Acetamidoethyl)phosphonic Acid Bis(TMS) Ester; AEAP-BTMS; Bis(trimethylsilyl) (2-acetamidoethyl)phosphonate; Acetylcysteamine Phosphonate Bis(TMS) Ester; TMS-Protected AEPA
EINECS	Contact for details

Quality Control

Our [2-(Acetylamino)Ethyl]Phosphonic Acid Bis(Trimethylsilyl) Ester is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.