Description

[1-(Acetylamino)Ethyl]Phosphonic Acid Bis(Trimethylsilyl) Ester CAS NO 55108-82-2 is a high-purity, silylated phosphonic acid derivative, serving as a crucial protected intermediate in advanced organic synthesis. Its primary value lies in enabling the controlled introduction of phosphonic acid functionality into complex molecules, a key step in developing bioactive compounds and specialty materials. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require precise and reliable building blocks for their synthetic workflows.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting bone metabolism or possessing antiviral properties.
• Agrochemical Synthesis: Used in the development of advanced herbicides, plant growth regulators, and other crop protection agents containing phosphonate groups.
• Ligand and Catalyst Precursor: Serves as a precursor for creating specialized phosphonate-based ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, surface modifiers, and metal-organic frameworks (MOFs) where phosphonic acid groups are required.
• Peptide Mimetics: Utilized in the design and synthesis of phosphonate-containing peptide analogs, which are stable to enzymatic degradation.
• Chemical Biology Probes: Acts as a protected synthon for creating activity-based probes and inhibitors for studying phosphonate-dependent enzymes.

Basic Information

Product Name	[1-(Acetylamino)Ethyl]Phosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	55108-82-2
Molecular Formula	C11H28NO4PSi2
Molecular Weight	325.48 g/mol
Synonyms	N-Acetyl-1-aminoethylphosphonic Acid Bis(trimethylsilyl) Ester; Phosphonic Acid, [1-(acetylamino)ethyl]-, bis(trimethylsilyl) ester; (1-Acetamidoethyl)phosphonic Acid Bis(TMS) Ester; Bis(trimethylsilyl) (1-acetamidoethyl)phosphonate; AEAP Bis(TMS) Ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of [1-(Acetylamino)Ethyl]Phosphonic Acid Bis(Trimethylsilyl) Ester undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development as well as scale-up manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity (typically by NMR and HPLC), identity confirmation, and impurity profile is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.